Which class of drugs is known for causing ototoxicity?

Aminoglycoside antibiotics are well-established for their potential to cause ototoxicity, which refers to damage to the inner ear, resulting in hearing loss or balance issues. This class of drugs can affect cochlear hair cells, leading to irreversible hearing impairment, particularly at high doses or with prolonged use. Given the importance of monitoring hearing function in patients receiving aminoglycosides, understanding their ototoxic effects is critical for healthcare providers.

Other drug classes mentioned, such as NSAIDs, antidepressants, and beta blockers, have not been consistently linked to ototoxic effects in the same manner. While some may have side effects that can impact overall health or have other risks, they are not primarily associated with auditory toxicity, making aminoglycosides the definitive choice in this context.